RAD23B anticorps

N° du produit ABIN7539777

Cet anticorps Souris Monoclonal détecte spécifiquement RAD23B dans WB, IHC, ICC et FACS. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour RAD23B anticorps (ABIN7539777)

Antigène: RAD23B (RAD23 Homolog B (RAD23B))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RAD23B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 6D2B3

Détail du produit anti-RAD23B anticorps

Fonction: RAD23B Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human RAD23B expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

FCM: 1/200 - 1/400

ICC: 1/100 - 1/400

Restrictions: For Research Use only

Stockage

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur RAD23B

Antigène: RAD23B (RAD23 Homolog B (RAD23B))

Autre désignation: RAD23B

Sujet: The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Poids moléculaire: 43.2 kDa

ID gène: 5887

UniProt: P54727

Pathways: Réparation de l'ADN