beta Arrestin 1 anticorps (AA 89-268)

N° du produit ABIN7539841

L’anticorps Souris Monoclonal anti-beta Arrestin 1 a été validé pour ELISA. Il convient pour détecter beta Arrestin 1 dans des échantillons de Humain.

Aperçu rapide pour beta Arrestin 1 anticorps (AA 89-268) (ABIN7539841)

Antigène: beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp beta Arrestin 1 est non-conjugé

Application: ELISA

Clone: 4E11B1

Détail du produit anti-beta Arrestin 1 anticorps

Épitope: AA 89-268

Fonction: ARRB1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human ARRB1 (AA: 89-268) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur beta Arrestin 1

Antigène: beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))

Autre désignation: ARRB1

Sujet: Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.

Poids moléculaire: 47 kDa

UniProt: P49407

Pathways: Positive Regulation of Peptide Hormone Secretion, Nuclear Hormone Receptor Binding, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction