Galectin 3 anticorps (PE)

N° du produit ABIN7540408

Cet anticorps anti-Galectin 3 est un anticorps Rat Monoclonal détectant Galectin 3 dans FACS et ICFC. Adapté pour Humain et Souris.

Aperçu rapide pour Galectin 3 anticorps (PE) (ABIN7540408)

Antigène: Galectin 3 (LGALS3)

Reactivité: Humain, Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Galectin 3 est conjugé à/à la PE

Application: Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)

Clone: M3-38

Détail du produit anti-Galectin 3 anticorps (PE)

Fonction: Anti-Galectin-3 PE

Specificité: The rat monoclonal antibody M3/38 recognizes an epitope within amino acids 40-100 in N-terminal domain of murine galectin 3, a 35 kDa lectin expressed both intracellularly, and after its secretion also on the cell surface.

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène: murine galectin-3

Isotype: IgG2a kappa

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 1-5 μg/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Détails sur Galectin 3

Antigène: Galectin 3 (LGALS3)

Autre désignation: Galectin-3

Sujet:

NCBI Full Gene Name: lectin, galactose binding, soluble 3

Description: Galectin-3 is a galactose-binding lectin, which modulates intercellular interactions and interactions of the cell with ECM, as well as it is a nuclear protein and a component of inner mitochondrial membrane. Galectin-3 binds IgE, and takes part in formation of immunological synapse. It is detected cytoplasmatically in adenomas and carcinomas by immunohistochemistry. It is expressed in colonic and intestinal epithelium, papillary and follicular carcinomas, neoplastic astrocytes, inflammatory macrophages, and some lymphocytes. Upregulation of galectin-3 is involved in cancer progression and metastasis.

Other names: Mac-2, GBP, Gal-3, L-34

Gene name: Lgals3

ID gène: 16854

UniProt: P16110

Pathways: Signalisation RTK