ADAM10 anticorps (APC)

N° du produit ABIN7540421

Cet anticorps Souris Monoclonal détecte spécifiquement ADAM10 dans FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour ADAM10 anticorps (APC) (ABIN7540421)

Antigène: ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ADAM10 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Clone: 11G2

Détail du produit anti-ADAM10 anticorps (APC)

Fonction: Anti-Hu CD156c APC

Specificité: The mouse monoclonal antibody 11G2 recognizes an extracellular/luminal epitope of CD156c, a type I transmembrane glycoprotein, serving as a zinc-dependent metalloprotease.

Aucune reactivité croisée: Souris

Purification: Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène: Jurkat cells

Isotype: IgG1 kappa

Information d'application

Indications d'application: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Détails sur ADAM10

Antigène: ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))

Autre désignation: CD156c

Sujet:

NCBI Full Gene Name: ADAM metallopeptidase domain 10

Description: CD156c is a type I transmembrane glycoprotein with a zinc-dependent metalloprotease activity. It serves as an endopeptidase of broad specificity, which is expressed mainly in thymus, liver, and muscles. Its expression can be induced in inflamed central nervous system, and in arthritic tissues. CD156c is involved in multiple sclerosis-associated myelin degradation. It also solubilizes various membrane proteins, including CD23, CD44, CD126, CD171, ephrin-A2, and other.

Other names: ADAM10, AD10, RAK, MADM, HsT18717

Gene name: ADAM10

ID gène: 102

UniProt: O14672

Pathways: Signalisation Notch, EGFR Signaling Pathway