CD70 anticorps (APC)

N° du produit ABIN7540450

Cet anticorps anti-CD70 est un anticorps Souris Monoclonal détectant CD70 dans FACS. Adapté pour Humain.

Aperçu rapide pour CD70 anticorps (APC) (ABIN7540450)

Antigène: CD70 (CD70 Molecule (CD70))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD70 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Clone: Ki-24

Détail du produit anti-CD70 anticorps (APC)

Fonction: Anti-Hu CD70 APC

Specificité: The mouse monoclonal antibody Ki-24 recognizes an extracellular epitope of CD70, an approximately 50 kDa type II transmembrane glycoprotein expressed on activated lymphocytes and some B cell leukemias.

Purification: Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène: human L428 cell line

Isotype: IgG3 kappa

Information d'application

Indications d'application: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Détails sur CD70

Antigène: CD70 (CD70 Molecule (CD70))

Autre désignation: CD70

Sujet:

NCBI Full Gene Name: CD70 Molecule

Description: CD70, also known as TNFSF7 or CD27L, is a 50 kDa type II transmembrane glycoprotein of the TNF superfamily. It is expressed mainly on activated lymphocytes, including NK cells, and forms trimeric structure. CD70 plays a role in T-cell activation, proliferation and differentiation, in enhancing the generation of cytolytic T cells, and in long-term maintenance of T cell memory. It is also involved in B cell differentiation induced by activated plasmacytoid dendritic cells, which also express CD70.

Other names: CD27L, TNFSF7, CD27 ligand, TNLG8A

Gene name: CD70

ID gène: 970

UniProt: P32970

Pathways: Cancer Immune Checkpoints