Gelsolin anticorps
Aperçu rapide pour Gelsolin anticorps (ABIN7540497)
Antigène
Voir toutes Gelsolin (GSN) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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N° du produit (Fournisseur)
- 200-301-p37
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Fournisseur
- Rockland
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Fonction
- Gelsolin Antibody
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Réactivité croisée (Details)
- This product reacts with human and rabbit.
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Purification
- Anti-Gelsolin antibody was purified from mouse ascites by protein A chromatography.
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Immunogène
- Gelsolin antibody was produced in mice by repeated immunizations with human plasma gelsolin.
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Isotype
- IgG1
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Indications d'application
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ELISA_Dilution: 1:10,000
Immunohistochemistry_Dilution: 1:100-1:500
Western_Blot_Dilution: 0.5-1 μg/mL
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Commentaires
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Anti-Gelsolin is tested for Immunohistochemistry -P, -F and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~85.7 kDa corresponding to the appropriate cell lysate or extract.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
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Reconstitution_Buffer: Neutral PBS
Reconstitution_Volume: 1.0 mL
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Buffer
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Buffer: 1.2 % sodium acetate
Stabilizer: 2 mg BSA
Preservative: 0.01 % (w/v) Sodium Azide -
Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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Date de péremption
- 12 months
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- Gelsolin (GSN)
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Autre désignation
- GSN
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Sujet
- AGEL, ADF, Brevin, Actin-depolymerizing factor,Gelsolin, a protein of leukocytes, platelets, and other cells, severs actin filaments in the presence of submicromolar calcium, thereby solating cytoplasmic actin gels. A gelsolin variant with 23 more N-terminal amino acids is a plasma component probably involved in the clearance of actin, the most abundant human protein, from the circulation. Gelsolin is located in 9q34. Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain. This antibody is suitable for researchers interested in cell research and cytoskeletal signaling research.
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ID gène
- 2934
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NCBI Accession
- NP_000168
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UniProt
- P06396
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Pathways
- Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, Autophagy
Antigène
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