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Recombinant CD33 (Gemtuzumab Biosimilar) anticorps

Cet anticorps Souris Chimeric détecte spécifiquement CD33 (Gemtuzumab Biosimilar) dans FACS et IF. Il présente une réactivité envers Humain.
N° du produit ABIN7542953

Aperçu rapide pour Recombinant CD33 (Gemtuzumab Biosimilar) anticorps (ABIN7542953)

Antigène

CD33 (Gemtuzumab Biosimilar)

Type d'anticorp

Recombinant Antibody

Reactivité

Humain

Hôte

  • 3
  • 2
  • 1
  • 1
Souris

Clonalité

  • 5
  • 2
Chimeric

Conjugué

  • 6
  • 1
Cet anticorp CD33 (Gemtuzumab Biosimilar) est non-conjugé

Application

  • 4
  • 2
  • 1
Flow Cytometry (FACS), Immunofluorescence (IF)

Clone

HP67-6
  • Fonction

    Anti-CD33 [hP67.6 (Gemtuzumab)], Mouse IgG1, kappa

    Specificité

    Recognises human CD33.

    Attributs du produit

    Original Species of Ab: Human

    Original Format of Ab: IgG4

    Purification

    Protein A affinity purified

    Immunogène

    Gemtuzumab was generated by huminization of the murine P67.6 clone, raised against CD33-transfected FMY9S5 cells of human origin. CD33 is a transmembrane receptor expressed on predominantly on cells of the myeloid lineage, but it can also be found on some lymphoid cells.

    Isotype

    IgG1 kappa
  • Indications d'application

    A human IgG4 variant conjugated to derivative of the cytotoxic drug calicheamicin gamma 1, N-acetylcalicheamicin dimethyl hydrazide, has been used as a therapeutic against acute myeloid leukemia. This antibody may also be used in flow cytometry and immunofluorescence.

    Commentaires

    This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG4 format, for improved compatibility with existing reagents, assays and techniques.

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % Proclin 300.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Antigène

    CD33 (Gemtuzumab Biosimilar)

    Classe de substances

    Biosimilar

    Sujet

    Siglec-3

    UniProt

    P20138
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