Recombinant CD40L (Ruplizumab Biosimilar) anticorps

N° du produit ABIN7542960

L’anticorps anti-CD40L (Ruplizumab Biosimilar) Chimeric Souris est utilisé pour la détection de CD40L (Ruplizumab Biosimilar) dans des échantillons de Humain. Il a été validé pour FACS, WB et BR.

Aperçu rapide pour Recombinant CD40L (Ruplizumab Biosimilar) anticorps (ABIN7542960)

Antigène: CD40L (Ruplizumab Biosimilar) (CD40LG (Ruplizumab Biosimilar))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Chimeric

Conjugué: Cet anticorp CD40L (Ruplizumab Biosimilar) est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Blocking Reagent (BR)

Clone: Hu5c8

Détail du produit anti-CD40L (Ruplizumab Biosimilar) anticorps

Fonction: Anti-CD40L [hu5c8 (Ruplizumab)], Mouse IgG2a, kappa

Specificité:

The antibody binds to CD40L with an IC50 of 0.845 μg/mL.

Application Notes original Clone: The antibody binds specifically to CD40L, a surface receptor expressed on activated T cells which acts as a costimulatory molecule to trigger immune responses. The antibody neutralises CD40L function, as it blocks the interaction between CD40 and CD40L. When injected into cynomolgus monkeys, the original therapeutic antibody was found to have a T1/2 of 531 ±155 hours.

Attributs du produit: This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Purification: Protein A affinity purified

Immunogène: Human CD40L

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

OriginalSpeciesName: Human

OriginalFormat: IgG1

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur CD40L (Ruplizumab Biosimilar)

Antigène: CD40L (Ruplizumab Biosimilar) (CD40LG (Ruplizumab Biosimilar))

Autre désignation: CD40L (Ruplizumab Biosimilar)

Classe de substances: Biosimilar

Sujet: CD154, CD40 ligand, tumour necrosis factor ligand superfamily member 5, TNFSF5, tumour necrosis factor related activation protein, TRAP

UniProt: P29965