Recombinant GDF8 (Lintuzumab Biosimilar) anticorps

N° du produit ABIN7543068

L’anticorps anti-GDF8 (Lintuzumab Biosimilar) Monoclonal Human est utilisé pour la détection de GDF8 (Lintuzumab Biosimilar) dans des échantillons de Humain. Il a été validé pour Func.

Aperçu rapide pour Recombinant GDF8 (Lintuzumab Biosimilar) anticorps (ABIN7543068)

Antigène: GDF8 (Lintuzumab Biosimilar)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Human

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Functional Studies (Func)

Clone: SGN-33

Détail du produit

Fonction: Anti-CD33 [SGN-33 (Lintuzumab)], Human IgG1, kappa

Specificité: This antibody is specific for human CD33, which is restricted to cells of the myelomonocytic lineage. CD33 but does not appear in abundance on normal cells, but is over-expressed in AML and other myeloproliferative diseases.

Attributs du produit:

Original Species of Ab: Human

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogène: This humanized antibody was prepared by combining the CDR regions of the murine anti-CD33 M195 with human framework and constant regions.

Isotype: IgG1 kappa

Information d'application

Indications d'application: In vitro, this antibody is capable of mediating ADCC against AML cells (Caron, 1998). Though shown to be safe in phase III trials, the use of this antibody in combination with induction chemotherapy did not result in a statistically significant improvement in response rate or survival in patients with refractory/relapsed AML (Feldman, 2005).

Commentaires:

NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détail du antigène

Antigène: GDF8 (Lintuzumab Biosimilar)

Autre désignation: CD33 (Lintuzumab Biosimilar)

Classe de substances: Biosimilar

Sujet: Sialic acid-binding Ig-like lectin 3, gp67, HuM195

UniProt: P20138