Recombinant GRIN2B anticorps

N° du produit ABIN7543080

L’anticorps anti-GRIN2B Monoclonal Souris est utilisé pour la détection de GRIN2B dans des échantillons de Rat. Il a été validé pour Crys.

Aperçu rapide pour Recombinant GRIN2B anticorps (ABIN7543080)

Antigène: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Type d'anticorp: Recombinant Antibody

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GRIN2B est non-conjugé

Application: Crystallization (Crys)

Clone: 17

Détail du produit anti-GRIN2B anticorps

Fonction: Anti-NMDA Receptor [17], Mouse IgG1, kappa

Specificité: Reacts specifically with rat GluN2B ATD.

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG

Purification: Protein A affinity purified

Immunogène: Monoclonal antibodies that bind rat GluN2B ATD were obtained by immunizing mice with the purified intact GluN1-GluN2B NMDA receptors. IgGs were purified from hybridoma cell culture supernatant by Protein-A Sepharose. Fab fragments have been prepared by papain proteolysis followed by re-chromatographing onto Protein-A Sepharose to remove Fc.

Isotype: IgG1 kappa

Information d'application

Indications d'application: This antibody has been used for the crystallisation of the NMDA receptor in the absence of an allosteric inhibitor at 2.9A (Tajima 2016).

Commentaires:

This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur GRIN2B

Antigène: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Autre désignation: Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B

Sujet: NMDAR, NMDA-R, Glutamate receptor

UniProt: Q00960

Pathways: Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity