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Recombinant DLL4 anticorps

Cet anticorps anti-DLL4 est un anticorps Souris Monoclonal détectant DLL4 dans ELISA, IHC, IF et BP. Adapté pour Humain.
N° du produit ABIN7543201

Aperçu rapide pour Recombinant DLL4 anticorps (ABIN7543201)

Antigène

Voir toutes DLL4 Anticorps
DLL4 (delta-Like 4 (DLL4))

Type d'anticorp

Recombinant Antibody

Reactivité

  • 59
  • 42
  • 15
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Humain

Hôte

  • 59
  • 19
  • 9
  • 5
  • 1
Souris

Clonalité

  • 60
  • 32
  • 1
Monoclonal

Conjugué

  • 56
  • 8
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp DLL4 est non-conjugé

Application

  • 46
  • 32
  • 18
  • 17
  • 13
  • 13
  • 9
  • 7
  • 7
  • 5
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Blocking Peptide (BP)

Clone

61B
  • Fonction

    Anti-DLL4 [61B], Mouse IgG2a, kappa

    Specificité

    This antibody is specific for the EGF-like 3 domain of Dll4.

    Attributs du produit

    Original Species of Ab: Mouse

    Original Format of Ab: IgG2a

    Purification

    Protein A affinity purified

    Immunogène

    The original antibody was generated by immunizing mice with soluble human Dll4-His protein.

    Isotype

    IgG2a kappa
  • Indications d'application

    U87MG and HT29 cells were immune-stained with this antibody (Zhou et al, 2015, pmid:26288060). This antibody is used for immunohistochemistry on U87MG and HT29 (Zhou et al, 2015, pmid:26288060). The 64Cu-chelator DOTA conjugated version of this antibody was used for the positron-emission tomography (PET) imaging of human glioblastoma and colorectal cancer xenografts (Zhou et al, 2015, pmid:26288060). This antibody was used for immunohistochemistry on spheroids and monolayers cells (US7906116). ELISA was performed with this antibody on Dll4 truncation mutants (US7906116). This antibody is able to block the Dll4-Notch1 interaction (US7906116).

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % Proclin 300.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Antigène

    DLL4 (delta-Like 4 (DLL4))

    Autre désignation

    DLL4

    Sujet

    Delta-like protein 4, Drosophila Delta homolog 4, Delta4

    UniProt

    Q9NR61

    Pathways

    Signalisation Notch
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