Recombinant DLL4 anticorps

N° du produit ABIN7543202

Cet anticorps Lapin Chimeric détecte spécifiquement DLL4 dans ELISA, IHC, IF et BP. Il présente une réactivité envers Humain.

Aperçu rapide pour Recombinant DLL4 anticorps (ABIN7543202)

Antigène: DLL4 (delta-Like 4 (DLL4))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp DLL4 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Blocking Peptide (BP)

Clone: 61B

Détail du produit anti-DLL4 anticorps

Fonction: Anti-DLL4 [61B], Rabbit IgG, kappa

Specificité: This antibody is specific for the EGF-like 3 domain of Dll4.

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG2a

Purification: Protein A affinity purified

Immunogène: The original antibody was generated by immunizing mice with soluble human Dll4-His protein.

Isotype: IgG kappa

Information d'application

Indications d'application: U87MG and HT29 cells were immune-stained with this antibody (Zhou et al, 2015, pmid:26288060). This antibody is used for immunohistochemistry on U87MG and HT29 (Zhou et al, 2015, pmid:26288060). The 64Cu-chelator DOTA conjugated version of this antibody was used for the positron-emission tomography (PET) imaging of human glioblastoma and colorectal cancer xenografts (Zhou et al, 2015, pmid:26288060). This antibody was used for immunohistochemistry on spheroids and monolayers cells (US7906116). ELISA was performed with this antibody on Dll4 truncation mutants (US7906116). This antibody is able to block the Dll4-Notch1 interaction (US7906116).

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur DLL4

Antigène: DLL4 (delta-Like 4 (DLL4))

Autre désignation: DLL4

Sujet: Delta-like protein 4, Drosophila Delta homolog 4, Delta4

UniProt: Q9NR61

Pathways: Signalisation Notch