Recombinant Estrogen Receptor alpha anticorps

N° du produit ABIN7543365

L’anticorps anti-Estrogen Receptor alpha Chimeric Lapin est utilisé pour la détection de Estrogen Receptor alpha dans des échantillons de Humain. Il a été validé pour ELISA.

Aperçu rapide pour Recombinant Estrogen Receptor alpha anticorps (ABIN7543365)

Antigène: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp Estrogen Receptor alpha est non-conjugé

Application: ELISA

Clone: 4E11

Détail du produit anti-Estrogen Receptor alpha anticorps

Fonction: Anti-Estrogen receptor [4E11], Rabbit IgG, kappa

Specificité: The antibody is specific for estrogen receptor ER-α36. The estrogen receptor ER-α36 is an estrogen receptor subtype mainly expressed on the cell membrane, it mediates the non-genomic estrogen signal pathway, and can inhibit the traditional estrogen signal pathway. It plays a vital role in the occurrence and development of diseases. For example its expression level is closely related to some biological indicators of cancer.

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG2b

Purification: Protein A affinity purified

Immunogène: The original antibody was generated by immunizing mice with estrogen receptor ER-alpha36.

Isotype: IgG kappa

Information d'application

Indications d'application: The antibody specifically recognized ER-α36 protein expressed by SUM159 cells, as confirmed by ELISA analysis (CN107987164).

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format for improved compatibility with existing reagents assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur Estrogen Receptor alpha

Antigène: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Autre désignation: Estrogen receptor

Sujet: ER, ERα36, ER-α36, hER-α36, ESR1, ER-alpha, NR3A1, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1, ER-alpha Estradiol receptor, Nuclear receptor subfamily 3 group A member 1

UniProt: P03372

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly