Recombinant CDX2 anticorps

N° du produit ABIN7543367

Cet anticorps Lapin Chimeric détecte spécifiquement CDX2 dans WB, ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour Recombinant CDX2 anticorps (ABIN7543367)

Antigène: CDX2 (Caudal Type Homeobox 2 (CDX2))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp CDX2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 12B6

Détail du produit anti-CDX2 anticorps

Fonction: Anti-CDX2 [12B6], Rabbit IgG, kappa

Specificité: The antibody recognises human CDX2. The CDX2 protein is a homeobox transcription factor expressed in the nuclei of intestinal epithelial cells, playing an essential role in the development and function of the digestive system.

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG2b

Purification: Protein A affinity purified

Immunogène: The original antibody was generated by immunizing a mouse with the CDX2-KLH protein.

Isotype: IgG kappa

Information d'application

Indications d'application: The antibody was used for immunohistochemistry on stomach adenocarcinoma, showing accurate staining location, clear staining, no non-specific staining, and clean background. Further, immunohistochemistry staining on stomach adenocarcinoma from 12B6 antibody and the commercial antibody, rabbit mono-ERP2764Y, were compared. Results showed the staining intensity of 12B6 antibody was significantly higher than those of ERP2764Y, showing 12B6 antibody is more sensitive. Moreover, the antibody and the commercial antibody TA347 were used for immunohistochemistry on appendix tissue. Results showed that the antibody (12B6) and the commercially available antibody (TA347) were simultaneously detected on the normal tissue chip, and the negative and positive detection results were consistent, indicating that the specificity of the antibody in normal tissue was equivalent to that of the commercially available antibody. The antibody detected human CDX2 by western blot analysis (CN113265000).

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format for improved compatibility with existing reagents assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur CDX2

Antigène: CDX2 (Caudal Type Homeobox 2 (CDX2))

Autre désignation: CDX2

Sujet: Homeobox protein CDX-2, CDX-3, Caudal-type homeobox protein 2, rabbit mono-ERP2764Y, TA347

UniProt: Q99626

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance