Recombinant TdT anticorps
Aperçu rapide pour Recombinant TdT anticorps (ABIN7543412)
Antigène
Voir toutes TdT (DNTT) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Anti-Terminal Deoxynucleotidyl Transferase [32D5], Rabbit IgG, kappa
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Specificité
- The antibody is specific for TdT. TdT catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.
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Attributs du produit
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Original Species of Ab: Mouse
Original Format of Ab: IgG2a
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Purification
- Protein A affinity purified
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Immunogène
- The original antibody was generated by immunizing mice with the recombinant TdT protein.
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Isotype
- IgG kappa
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Indications d'application
- The antibody specifically detected TDT protein in Western blot analysis. The antibody 32D5 and the commercial antibody SEN28 were used to stain lymphoma and thymus. Results showed the antibody specificity is comparable to the commercial antibody. Further, the sensitivity of the antibody 32D5 was higher than the commercial antibody. The antibody and the commercially available antibody TA347 were simultaneously detected on the normal tissue chip, indicating that the specificity of the antibody in normal tissue was equivalent to that of the commercially available antibody (CN113265003A).
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Commentaires
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format for improved compatibility with existing reagents assays and techniques.
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))
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Autre désignation
- Terminal Deoxynucleotidyl Transferase
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Sujet
- TdT, DNA nucleotidylexotransferase, Terminal addition enzyme, Terminal deoxynucleotidyltransferase, Terminal transferase, CGMCC NO 20777
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UniProt
- P04053
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Pathways
- Réparation de l'ADN
Antigène
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