Recombinant Progesterone Receptor anticorps

N° du produit ABIN7543415

Cet anticorps Souris Chimeric détecte spécifiquement Progesterone Receptor dans WB, IHC et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour Recombinant Progesterone Receptor anticorps (ABIN7543415)

Antigène: Progesterone Receptor (PGR)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Chimeric

Conjugué: Cet anticorp Progesterone Receptor est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 14B3

Détail du produit anti-Progesterone Receptor anticorps

Fonction: Anti-Progesterone Receptor [14B3], Mouse IgG1, kappa

Specificité: The antibody is specific for PR protein. PR is a protein molecule, a cellular core receptor belonging to a steroidal superfamily, which can be bonded to the corresponding hormone to form a hormone-receptor complex, enabling hormones to exert their biological effects.

Attributs du produit:

Original Species of Ab: Rabbit

Original Format of Ab: IgG

Purification: Protein A affinity purified

Immunogène: The original antibody was generated by immunizing rabbits with PR protein.

Isotype: IgG1 kappa

Information d'application

Indications d'application: The specificity of the original format of the antibody was confirmed by ELISA analysis (affinity constant of 1.82 x 10^10 M-1). The antibody specifically detected PR protein in Western blot analysis. The antibody 14B3 and the commercial antibody 1E2 were used to stain breast cancer and endometrial. Results showed the antibody specificity is comparable to the commercial antibody. Further, the sensitivity of the antibody 14B3 was higher than the commercial antibody (CN113583132A).

Commentaires:

This chimeric mouse antibody was made using the variable domain sequences of the original Rabbit IgG format for improved compatibility with existing reagents assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur Progesterone Receptor

Antigène: Progesterone Receptor (PGR)

Autre désignation: Progesterone Receptor

Sujet: PR, Nuclear receptor subfamily 3 group C member 3

UniProt: P06401

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration