Recombinant Ferritin anticorps

N° du produit ABIN7543449

L’anticorps anti-Ferritin Chimeric Lapin est utilisé pour la détection de Ferritin dans des échantillons de Humain. Il a été validé pour ELISA.

Aperçu rapide pour Recombinant Ferritin anticorps (ABIN7543449)

Antigène: Ferritin (FE)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp Ferritin est non-conjugé

Application: ELISA

Clone: F11

Détail du produit anti-Ferritin anticorps

Fonction: Anti-Ferritin [F11 (HSF102)], Rabbit IgG, kappa

Specificité:

This antibody binds human ferritin. This protein catalyzes the oxidation of ferrous iron(II) to ferric iron(III) and stores iron in a soluble, non-toxic, readily available form. Ferritin is important for iron homeostasis.

Application Notes original Clone: The binding characterization of this antibody towards human spleen ferritin was done using ELISA. This antibody was also reported to show binding affinity for protein A. Binding of this antibody to ferritin causes antigen-induced conformational changes in the antibody and reduces its affinity for protein A (PMID: 9776583).

Attributs du produit: This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Purification: Protein A affinity purified

Immunogène: The original antibody was generated by immunizing female Balb/c mice with ferritin extracted from human spleen cells.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

OriginalSpeciesName: Mouse

OriginalFormat: IgG2a

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur Ferritin

Antigène: Ferritin (FE)

Autre désignation: Ferritin

Sujet: FTMT, FTL, FTH1, Ferritin mitochondrial, B8

UniProt: Q8N4E7

Pathways: Transition Metal Ion Homeostasis