CD72 anticorps (FITC)

N° du produit ABIN7566559

Cet anticorps Souris Monoclonal détecte spécifiquement CD72 dans FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour CD72 anticorps (FITC) (ABIN7566559)

Antigène: CD72 (CD72 Molecule (CD72))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD72 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Clone: 3F3

Détail du produit anti-CD72 anticorps (FITC)

Fonction: FITC Anti-Human CD72 Antibody[3F3]

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.
FCM: 5 µL/test

Commentaires:

Matching Isotype Control: (ABIN7469794)

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Stock: 4 °C

Stockage commentaire: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Date de péremption: 12 months

Détails sur CD72

Antigène: CD72 (CD72 Molecule (CD72))

Autre désignation: CD72

Sujet: Lyb-2,Ly-19.2,Ly-32.2,CD72 is a 39-43 kD type II membrane glycoprotein. It is a disulfide-linked homodimer belonging to C-type lectin family. CD72 is a pan-B cell marker expressed on pre-pre-B cells throughout B cell differentiation with the exception of plasma cells. It is also expressed on follicular dendritic cells, splenic red pulp macrophages (but not on peripheral blood monocytes), and liver Kupffer cells. CD72, a negative coreceptor of B cells, contains immunoreceptor tyrosine-based inhibitory motifs in the cytoplasmic domain which has been shown to recruit the tyrosine phosphatase SHP-1. Ligation of CD72 with its ligand regulates CD72 tyrosine dephosphorylation and SHP-1 dissociation to promote B cell activation and proliferation. CD100 and CD5 have been shown to be CD72 ligands. The CD100-CD72 interaction plays a role in maintenance of B cell homeostasis.

ID gène: 971

UniProt: P21854

Pathways: BCR Signaling