CD22 anticorps (Elab Fluor®700)

N° du produit ABIN7566715

Cet anticorps Souris Monoclonal détecte spécifiquement CD22 dans FACS. Il présente une réactivité envers Souris.

Aperçu rapide pour CD22 anticorps (Elab Fluor®700) (ABIN7566715)

Antigène: CD22 (CD22 Molecule (CD22))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD22 est conjugé à/à la Elab Fluor®700

Application: Flow Cytometry (FACS)

Clone: Cy34-1

Détail du produit anti-CD22 anticorps (Elab Fluor®700)

Fonction: Elab Fluor®700 Anti-Mouse CD22 Antibody[Cy34.1]

Isotype: IgG1, kappa

Information d'application

Indications d'application: Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10 cells in 100 μL volume].

Commentaires:

Matching Isotype Control: E-AB-F09793M1

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Stock: 4 °C

Stockage commentaire: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Date de péremption: 12 months

Détails sur CD22

Antigène: CD22 (CD22 Molecule (CD22))

Autre désignation: CD22

Sujet: Siglec2,B-cell receptor CD22,B-lymphocyte cell adhesion molecule,BL-CAM,CD22,Cd22,Lyb-8,Sialic acid-binding Ig-like lectin 2,Siglec-2,T-cell surface antigen Leu-14,The Cy34.1 monoclonal antibody specifically binds to the B-lymphocyte differentiation antigen CD22 on strains having the Lyb-8.2 alloantigen (e.g., A, BALB/c, CBA, C3H/He, C57BL, C57L, C58, SJL, SWR, but not AKR, DBA/1, DBA/2, NZB, PL). CD22 is expressed at high levels on mature peripheral B lymphocytes (follicular and marginal zone), B-1 cells (CD5+ B cells), and plasma cells. It is a member of the Ig gene superfamily and associates with the B-cell antigen receptor. Its sialic acid- binding immunoglobulin-like lectin (siglec) extracellular region mediates B-cell adhesion to ligands on endothelial cells in the bone marrow. Its intracellular domain is phosphorylated after cross-linking of antigen receptor or MHC class II antigen. It is involved in negative regulation of B-cell activation and protection from autoimmunity. B-cell proliferative responses to LPS or anti-mouse Ig μ chain are augmented in the presence of Cy34.1 mAb.

ID gène: 12483

UniProt: P35329