SELPLG anticorps (Elab Fluor®700)

N° du produit ABIN7566722

L’anticorps Rat Monoclonal anti-SELPLG a été validé pour FACS. Il convient pour détecter SELPLG dans des échantillons de Souris.

Aperçu rapide pour SELPLG anticorps (Elab Fluor®700) (ABIN7566722)

Antigène: SELPLG (Selectin P Ligand (SELPLG))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp SELPLG est conjugé à/à la Elab Fluor®700

Application: Flow Cytometry (FACS)

Clone: 4RA10

Détail du produit anti-SELPLG anticorps (Elab Fluor®700)

Fonction: Elab Fluor®700 Anti-Mouse CD162 Antibody[4RA10]

Isotype: IgG1, kappa

Information d'application

Indications d'application: Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.

Commentaires:

Matching Isotype Control: E-AB-F09822M1

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Stock: 4 °C

Stockage commentaire: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Date de péremption: 12 months

Détails sur SELPLG

Antigène: SELPLG (Selectin P Ligand (SELPLG))

Autre désignation: CD162

Sujet: CD162,P-selectin glycoprotein ligand 1,PSGL-1,Selectin P ligand,Selplg,The 4RA10 antibody reacts with the N-terminal functional peptide of CD162 (P-selectin glycoprotein ligand-1, PSGL-1), encoded by the Selpl gene. PSGL-1 is expressed on the cell surface as a homodimer of approximately 230 kDa. In the mouse, Selpl mRNA is detected in most tissues, with high levels found in hematopoietic cells, brain, and adipose tissue. Flow cytometric analyses have revealed CD162 expression on bone marrow-derived mast and dendritic cells, splenic leukocytes, platelets, peripheral blood neutrophils, and neutrophil and T-cell lines. PSGL-1 is a ligand for P-selectin (CD62P) and is involved in leukocyte rolling, the migration of leukocytes into inflamed tissues, and responses to vascular injury. It is a sialomucin that must be specifically sialylated, fucosylated, and sulfated to bind P-selectin. There is also evidence that other ligands for PSGL-1 and CD62P may exist. 4RA10 mAb is reported to block the binding of mouse leukocytes to CD62P and CD62L.

ID gène: 20345

UniProt: Q62170