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SELPLG anticorps (Elab Fluor®700)

Cet anticorps Rat Monoclonal détecte spécifiquement SELPLG dans FACS. Il présente une réactivité envers Souris.
N° du produit ABIN7566724

Aperçu rapide pour SELPLG anticorps (Elab Fluor®700) (ABIN7566724)

Antigène

Voir toutes SELPLG Anticorps
SELPLG (Selectin P Ligand (SELPLG))

Reactivité

  • 88
  • 45
  • 22
  • 1
  • 1
  • 1
Souris

Hôte

  • 78
  • 32
  • 23
  • 2
Rat

Clonalité

  • 66
  • 64
  • 3
Monoclonal

Conjugué

  • 45
  • 7
  • 7
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp SELPLG est conjugé à/à la Elab Fluor®700

Application

  • 78
  • 73
  • 34
  • 26
  • 21
  • 16
  • 11
  • 9
  • 7
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Clone

4RA10
  • Fonction

    Elab Fluor®700 Anti-Mouse CD162 Antibody[4RA10]

    Isotype

    IgG1, kappa
  • Indications d'application

    Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10 cells in 100 μL volume].

    Commentaires

    Matching Isotype Control: E-AB-F09823M1

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

    Stock

    4 °C

    Stockage commentaire

    This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

    Date de péremption

    12 months
  • Antigène

    SELPLG (Selectin P Ligand (SELPLG))

    Autre désignation

    CD162

    Sujet

    CD162,P-selectin glycoprotein ligand 1,PSGL-1,Selectin P ligand,Selplg,The 4RA10 antibody reacts with the N-terminal functional peptide of CD162 (P-selectin glycoprotein ligand-1, PSGL-1), encoded by the Selpl gene. PSGL-1 is expressed on the cell surface as a homodimer of approximately 230 kDa. In the mouse, Selpl mRNA is detected in most tissues, with high levels found in hematopoietic cells, brain, and adipose tissue. Flow cytometric analyses have revealed CD162 expression on bone marrow-derived mast and dendritic cells, splenic leukocytes, platelets, peripheral blood neutrophils, and neutrophil and T-cell lines. PSGL-1 is a ligand for P-selectin (CD62P) and is involved in leukocyte rolling, the migration of leukocytes into inflamed tissues, and responses to vascular injury. It is a sialomucin that must be specifically sialylated, fucosylated, and sulfated to bind P-selectin. There is also evidence that other ligands for PSGL-1 and CD62P may exist. 4RA10 mAb is reported to block the binding of mouse leukocytes to CD62P and CD62L.

    ID gène

    20345

    UniProt

    Q62170
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