CCR7 anticorps (Elab Fluor®700)

N° du produit ABIN7566897

Cet anticorps anti-CCR7 est un anticorps Souris Monoclonal détectant CCR7 dans FACS. Adapté pour Humain.

Aperçu rapide pour CCR7 anticorps (Elab Fluor®700) (ABIN7566897)

Antigène: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CCR7 est conjugé à/à la Elab Fluor®700

Application: Flow Cytometry (FACS)

Clone: G043H7

Détail du produit anti-CCR7 anticorps (Elab Fluor®700)

Fonction: Elab Fluor®700 Anti-Human CD197/CCR7 Antibody[G043H7]

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.

Commentaires:

Matching Isotype Control: E-AB-F09802M1

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Stock: 4 °C

Stockage commentaire: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Date de péremption: 12 months

Détails sur CCR7

Antigène: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Autre désignation: CD197

Sujet: EBI1, EVI1,CCR-7,CDw197,CMKBR7,CCR7, also known as CD197, is a chemokine receptor that binds CCL19 and CCL21. CCR7 and its ligands link innate and adaptive immunity by affecting interactions between T cells and dendritic cells and their downstream effect. Naive T cells enter the lymph node through high endothelial venules, which express CCL21. Dendritic cells and macrophages enter the lymph node through afferent lymphatics. The encounter of T cells and dendritic cells in the T cell zone is CCR7-dependent. In addition, during immunological surveillance, B cells recirculate between B-cell-rich compartments (follicles or B cell zones) in secondary lymphoid organs, surveying for antigen. After antigen binding, B cells move to the boundary of B and T zones to interact with T-helper cells, this B cell migration is directed by CCR7 and its ligands. CCR7-positive cancer cell expression has been associated with lymph node metastasis.

ID gène: 1236

UniProt: P32248

Pathways: Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process