ENPP2 anticorps

N° du produit ABIN7581209

Cet anticorps Chèvre Polyclonal détecte spécifiquement ENPP2 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour ENPP2 anticorps (ABIN7581209)

Antigène: ENPP2 (Ectonucleotide Pyrophosphatase / phosphodiesterase 2 (ENPP2))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp ENPP2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ENPP2 anticorps

Fonction: Goat polycolonal antibody targeting human Autotaxin (ATX)

Specificité: Anti-ATX antibody recognizes endogenous human ATX and is predicted to recognize rat, mouse, horse, and feline ATX based on amino acid conservation.

Purification: affinity purified

Immunogène: ATX peptide

Isotype: IgG

Information d'application

Indications d'application: WB – 1:1000, ELISA – 1:1000 Other in vitro and cellular applications are possible using this antibody, but have not been verified.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4

Stock: 4 °C,-20 °C

Stockage commentaire: Antibody is stable for up to 1 year at -20°C. Antibody is stable at 4°C for up to 60 days. Avoid repeated freeze/thaw cycles.

Détails sur ENPP2

Antigène: ENPP2 (Ectonucleotide Pyrophosphatase / phosphodiesterase 2 (ENPP2))

Autre désignation: Autotaxin

Sujet: ATX, also known as ENPP2, cleaves choline from lysophosphatidylcholine forming lysophosphatidic acid (LPA), a potent mitogen that has been implicated in the pathophysiology of ovarian cancer. ATX has been demonstrated to increase cell motility, neovascularization, proliferation, and aggressiveness of tumors and is upregulated in numerous cancer lineages (non-small cell lung , glioma, mammary carcinoma, renal cell carcinoma, hepatocellular carcinoma). In addition, dysregulation of the ATX/LPA pathway is central to the pathophysiology of idiopathic pulmonary fibrosis, rheumatoid arthritis, and other inflammatory diseases.