Cet anticorps anti-PIKFYVE Polyclonal Lapin (ABIN7581220) détecte spécifiquement PIKFYVE dans WB, IP et ICC.
L’anticorps est réactif avec des échantillons de Différentes espèces.
Rabbit polyclonal antibody to murine PIKfyve with reactivity to mouse/rat and human PIKfyve
Specificité
The PIKfyve antibody is directed at an N-terminal region of PIKfyve and detects mammalian forms of PIKfyve with an expected molecular weight of approximately 237 kDa.
IF/ICC – 2-5 ug/mL Western – 1.0 ug/mL Immunoprecipitation – 1.0 ug/mL Other in vitro and cellular applications are possible using this antibody, but have not been verified.
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS, pH 7.4
Stock
4 °C,-20 °C
Stockage commentaire
protect from direct light and store at 4°C for up to 30 days. For long term storage, aliquot and store at -80°C. Avoid repeated freeze/thaw cycles.
PIKfyve (aka PIP5K3) is an approximately 237 kDa lipid kinase enzyme. It is primarily found on early endosomes where it synthesizes PI(3,5)P2 from membrane-associated PI(3)P. Endosomal PIKfyve forms a complex with ArPIKfyve (Vac14) and Sac3 to regulate fusion, transport, and export of endosomes in the cell. PIKfyve also has protein kinase activity in the form of self-regulatory autophosphorylation.