KISS1R anticorps (Extracellular) (FITC)

N° du produit ABIN7582049

L’anticorps Lapin Polyclonal anti-KISS1R a été validé pour FACS et LCI. Il convient pour détecter KISS1R dans des échantillons de Humain.

Aperçu rapide pour KISS1R anticorps (Extracellular) (FITC) (ABIN7582049)

Antigène: KISS1R (KISS1 Receptor (KISS1R))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KISS1R est conjugé à/à la FITC

Application: Flow Cytometry (FACS), Live Cell Imaging (LCI)

Détail du produit anti-KISS1R anticorps (FITC)

Épitope: AA 292-305, Extracellular

Fonction: A Rabbit Polyclonal Antibody to KISS1 Receptor (GPR54) (extracellular) conjugated to the fluorescent dye FITC

Séquence: (C)GSWHPRSYAA YALK

Specificité: 3rd extracellular loop

Homologie: Rat - 13 out of 14 amino acid residues identical,Mouse - 12 out of 14 amino acid residues identical

Attributs du produit: Anti-KISS1 Receptor (GPR54) (extracellular) Antibody (ABIN7043294, ABIN7044548 and ABIN7044549) is a highly specific antibody directed against an epitope of human KISS1 receptor. The antibody can be used in western blot, immunohistochemistry and flow cytometry applications. It has been designed to recognize KISS1R from human, rat, and mouse samples. Anti-KISS1 Receptor (GPR54) (extracellular)-FITC Antibody (ABIN7043294, ABIN7044548 and ABIN7044549-F) is directly conjugated to fluorescein isothiocyanate (FITC) fluorophore. This conjugated antibody has been developed to be used in immunofluorescent applications such as direct flow cytometry and live cell imaging.

Purification: Affinity purified on immobilized antigen.

Immunogène: (C)GSWHPRSYAAYALK, corresponding to amino acid residues 292-305 of human KISS1R

Isotype: IgG

Information d'application

Indications d'application:

Antigen preadsorption control: 1 μg peptide per 1 μg antibody

Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A

Application Dilutions Western blot wb: N/A

Commentaires:

Negative Control: (ABIN7582044)

Blocking Peptide: (ABIN7235833)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 50 μL double distilled water (DDW).

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 1 % BSA with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Détails sur KISS1R

Antigène: KISS1R (KISS1 Receptor (KISS1R))

Autre désignation: KISS1R

Sujet: Kisspeptin receptor, KISS1R, Metastin receptor, AXOR12, G-Protein Coupled Receptor 54,The kisspeptin receptor (KISS1R, GPCR54) is a member of the G-protein coupled receptor superfamily. KISS1R natural ligands are peptides called kisspeptins which are encoded by the Kiss1 gene. The Kiss1 gene was originally discovered by Hershey scientists who named it after their famous chocolate, the "Kiss".The kisspeptins, acting through KISS1R, were found to be potent inhibitors of metastasis in a variety of cancer cell types including thyroid and pancreatic cancer cells. KISS1R and kisspeptins are involved in the direct regulation of the reproductive neuroendocrine axis.KISS1R is widely distributed throughout the brain, where it is most highly expressed in the hypothalamic and amygdaloid nuclei. High expression was also found in the pancreas and placenta. Lower-level expression was found in a variety of other peripheral tissues including peripheral blood leukocytes, kidney, lung, testes, spleen, thymus, adrenal glands and lymph nodes.1-3

ID gène: 84634

UniProt: Q969F8