NOS1 anticorps

N° du produit ABIN7595322

L’anticorps Poulet Polyclonal anti-NOS1 a été validé pour WB et IHC. Il convient pour détecter NOS1 dans des échantillons de Humain.

Aperçu rapide pour NOS1 anticorps (ABIN7595322)

Antigène: NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))

Reactivité: Humain

Hôte: Poulet

Clonalité: Polyclonal

Conjugué: Cet anticorp NOS1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-NOS1 anticorps

Fonction: Chicken antibody to nNOS

Specificité: Specific for nNOS

Réactivité croisée: Humain, Marmoset, Souris, Rat

Réactivité croisée (Details): Other species not yet tested.

Purification: Purified IgY

Immunogène: A synthetic peptide from human nNOS conjugated to blue carrier protein was used as the antigen. The peptide is homologous in mouse and shares 96% identity with rat's sequence.

Isotype: IgY

Information d'application

Indications d'application: IHC WB. A dilution of 1: 500 is recommended. The optimal dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8C for a shorter term.

Date de péremption: 12 months

Détails sur NOS1

Antigène: NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))

Autre désignation: nNOS

Sujet: FUNCTION: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system NO displays many properties of a neurotransmitter. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum. SUBCELLULAR LOCATION: Cell membrane sarcolemma, Peripheral membrane protein. Cell projection dendritic spine. Note=In skeletal muscle it is localized beneath the sarcolemma of fast-twitch muscle fiber by associating with the dystrophin glycoprotein complex. In neurons enriched in dendritic spines. TISSUE SPECIFICITY: Isoform N-NOS-1 is expressed in brain and colorectum. Found in the Auerbach's plexus of the enteric nervous system. Isoform PNNOS is expressed in the penis urethra prostate and skeletal muscle and coexists with the cerebellar nnos in the pelvic plexus bladder and liver and is detectable in the cerebellum.

Pathways: Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction