PINK1 anticorps (AA 112-496) (FL490)

N° du produit ABIN7595423

Cet anticorps Souris Monoclonal détecte spécifiquement PINK1 dans IHC et ICC. Il présente une réactivité envers Humain.

Aperçu rapide pour PINK1 anticorps (AA 112-496) (FL490) (ABIN7595423)

Antigène: PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PINK1 est conjugé à/à la FL490

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: N4-15

Détail du produit anti-PINK1 anticorps (FL490)

Épitope: AA 112-496

Fonction: Anti-Pink1 PTEN Induced Putative Kinase 1 Antibody FL490 Conjugate

Specificité: No off-targets reported

Réactivité croisée: Humain, Souris, Rat

Attributs du produit:

Description: Our Anti-Pink1 PTEN induced putative kinase 1 mouse monoclonal primary antibody is produced in-house from hybridoma clone N4/15. It detects human, mouse, and rat Pink1 PTEN induced putative kinase 1, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Manufacturer Comment: We produce our Pink1 PTEN induced putative kinase 1 mouse monoclonal primary antibody from hybridoma clone N4/15. It is great in IHC, ICC and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Pureté: > 90 % specific antibody

Immunogène: Fusion protein amino acids 112-496 of human Pink1 (accession number NP_115785) produced recombinantly in E. Coli

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Date de péremption: 12 months

Détails sur PINK1

Antigène: PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

Autre désignation: Pink1 PTEN induced putative kinase 1

Sujet:

Synonyms: Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)

Target Description: PTEN Induced Kinase 1 is encoded by the gene PINK1. PINK1 is a member of the protein kinase superfamily, Ser/Thr protein kinase family. PINK1 is a serine/threonine protein kinase that protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. PINK1 is highly expressed in the heart, skeletal muscle, and testis. Diseases associated with PINK1 include Parkinson Disease 6, Autosomal Recessive Early-Onset and Parkinson Disease 2, Autosomal Recessive Juvenile.

Gene Name Alternatives: PINK1

Poids moléculaire: 63 kDa

Pathways: Autophagy