CASK anticorps (AA 318-415) (FL490)

N° du produit ABIN7595444

Cet anticorps Souris Monoclonal détecte spécifiquement CASK dans IHC et ICC. Il présente une réactivité envers Humain.

Aperçu rapide pour CASK anticorps (AA 318-415) (FL490) (ABIN7595444)

Antigène: CASK (Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CASK est conjugé à/à la FL490

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: K56A-50

Détail du produit anti-CASK anticorps (FL490)

Épitope: AA 318-415

Fonction: Anti-CASK Antibody FL490 Conjugate

Specificité: No off-targets reported

Réactivité croisée: Poulet, Humain, Souris, Rat, Xenopus laevis, Poisson zèbre (Danio rerio)

Attributs du produit:

Description: Our Anti-CASK mouse monoclonal primary antibody is produced in-house from hybridoma clone K56A/50. It is KO validated, detects chicken, human, mouse, rat, Xenopus, and zebrafish CASK, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Manufacturer Comment: We produce our CASK mouse monoclonal primary antibody from hybridoma clone K56A/50. It is great in IHC, ICC and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Pureté: > 90 % specific antibody

Immunogène: Fusion protein amino acids 318-415 of rat CASK/Lin2 (accession number Q62915) produced recombinantly in E. Coli

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Date de péremption: 12 months

Détails sur CASK

Antigène: CASK (Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK))

Autre désignation: CASK

Sujet:

Synonyms: Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)

Target Description: Calcium/Calmodulin-Dependent Serine Protein Kinase or CASK scaffolding protein is encoded by the gene CASK. CASK is a member of the MAGUK (membrane-associated guanylate kinase) protein family. CASK is a a calcium/calmodulin-dependent serine protein kinase. CASK is found in many different tissues including kidney, lung, liver and brain. In the brain, CASK protein is located at synapses. CASK acts as a multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Mutations in this gene are associated with FG syndrome 4, microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked intellectual disability.

Gene Name Alternatives: CASK LIN2

Poids moléculaire: 100 kDa

Pathways: Synaptic Vesicle Exocytosis