NFASC anticorps (Intracellular) (FL490)

N° du produit ABIN7595517

L’anticorps Souris Monoclonal anti-NFASC a été validé pour IHC et ICC. Il convient pour détecter NFASC dans des échantillons de Rat.

Aperçu rapide pour NFASC anticorps (Intracellular) (FL490) (ABIN7595517)

Antigène: NFASC (Neurofascin (NFASC))

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NFASC est conjugé à/à la FL490

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: L11A-41

Détail du produit anti-NFASC anticorps (FL490)

Épitope: Intracellular

Fonction: Anti-Pan-Neurofascin Antibody FL490 Conjugate

Specificité: No off-targets reported

Réactivité croisée: Humain, Rat

Attributs du produit:

Description: Our Anti-Pan-Neurofascin mouse monoclonal primary antibody is produced in-house from hybridoma clone L11A/41. It detects human and rat Pan-Neurofascin, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Manufacturer Comment: We produce our Pan-Neurofascin mouse monoclonal primary antibody from hybridoma clone L11A/41. It is great in IHC, ICC and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Pureté: > 90 % specific antibody

Immunogène: Fusion protein 1066-1174 (intracellular domain common to NF-155 and NF-186) of rat NF-155 (accession number AAL27854) produced recombinantly in E. Coli

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Date de péremption: 12 months

Détails sur NFASC

Antigène: NFASC (Neurofascin (NFASC))

Autre désignation: Neurofascin

Sujet:

Synonyms: Neurofascin NF-155 NF-186

Target Description: Neurofascin is encoded by the gene NFASC. Two major isoforms of NeuroFascin are expressed as a result of alternative splicing, NF186 and NF155. These proteins are expressed in the central nervous system. In brain, NF186 is expressed at Nodes of Ranvier andNF155 is expressed in unmyelinated axons. Neuofascin plays a role in cell adhesion and is thought to be involved in processes such as neurite extension, synaptogenesis and myelination. Diseases associated with this gene include Demyelinating Polyneuropathy.

Gene Name Alternatives: Nfasc

Poids moléculaire: 155, 186 kDa (plus additional bands on immunoblot)

Pathways: Cell-Cell Junction Organization