HCN1 anticorps (AA 778-910)

N° du produit ABIN7595944

Cet anticorps anti-HCN1 est un anticorps Souris Monoclonal détectant HCN1 dans WB, IHC, IP, ICC et IEM. Adapté pour Rat.

Aperçu rapide pour HCN1 anticorps (AA 778-910) (ABIN7595944)

Antigène: HCN1 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1))

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HCN1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunoelectron Microscopy (IEM)

Clone: N70-28

Détail du produit anti-HCN1 anticorps

Épitope: AA 778-910

Fonction: Anti-HCN1 Antibody

Specificité: No off-targets reported for HCN2

Réactivité croisée: Gerbille, Humain, Souris, Non-Human Primate, Rat

Attributs du produit:

Description: Our Anti-HCN1 mouse monoclonal primary antibody is produced in-house from hybridoma clone N70/28. It is KO validated, detects human, mouse, and rat HCN1, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

Manufacturer Comment: We produce our HCN1 mouse monoclonal primary antibody from hybridoma clone N70/28. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.

Pureté: > 90 % specific antibody

Immunogène: Fusion protein amino acids 778-910 (cytoplasmic C-terminus) of rat HCN1 (accession number Q9JKB0), Mouse: 96% identity (128/133 amino acids identical) produced recombinantly in E. Coli

Isotype: IgG1

Information d'application

Indications d'application:

Dilution Range: IP: 10 μg

Dilution Range: IHC: 1:500

Dilution Range: ICC: 1:100

Dilution Range: WB: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.38

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Date de péremption: 24 months

Détails sur HCN1

Antigène: HCN1 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1))

Autre désignation: HCN1

Sujet:

Synonyms: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

Target Description: HCN1 is a member of the hyperpolarization-activated cyclic nucleotide gated channel family, also known as pacemaker channels. This family has a role in rhythmic activity of the heart and firing neurons. HCN channels are made up of four subunits, HCN1-4 and can be formed in multiple combinations. HCN1 is found in the hippocampus, neocortex, and cerebellar cortex of brain. Alterations in this protein have been implicated in the disease early infantile epileptic encephalopathy.

Gene Name Alternatives: Hcn1

Poids moléculaire: 100 kDa

Pathways: Asymmetric Protein Localization