EPO anticorps (AA 28-193)

N° du produit ABIN7596017

Cet anticorps anti-EPO est un anticorps Souris Monoclonal détectant EPO dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour EPO anticorps (AA 28-193) (ABIN7596017)

Antigène: EPO (Erythropoietin (EPO))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EPO est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: AT1C12

Détail du produit anti-EPO anticorps

Épitope: AA 28-193

Fonction: Human Erythropoietin/EPO antibody

Purification: protein-A affinity chromatography

Immunogène: Recombinant human Erythropoietin (28-193aa) purified from insect cell

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycero

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Détails sur EPO

Antigène: EPO (Erythropoietin (EPO))

Autre désignation: Erythropoietin/EPO

Classe de substances: Hormone

Sujet: EPO, also known as erythropoietin, is a glycoprotein hormone in the type I cytokine family and is related to thrombopoietin. Its three N-glycosylation sites, four alpha helices, and N- to C-terminal disulfide bond are conserved across species. It is primarily produced in the kidney by a population of fibroblast-like cortical interstitial cells adjacent to the proximal tubules. This protein can be found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. It also has neuroprotective activity against a variety of potential brain injuries and anti-apoptotic functions in several tissue types.

NCBI Accession: NP_000790

Pathways: Signalistation JAK/STAT, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity