TLR7 anticorps (AA 451-500)

N° du produit ABIN7596035

Cet anticorps anti-TLR7 est un anticorps Monoclonal produit chez le Souris, détectant TLR7 dans WB, ELISA et FACS. Convient pour Humain.

Aperçu rapide pour TLR7 anticorps (AA 451-500) (ABIN7596035)

Antigène: TLR7 (Toll-Like Receptor 7 (TLR7))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TLR7 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Clone: 4F4

Détail du produit anti-TLR7 anticorps

Épitope: AA 451-500

Fonction: Human TLR7 antibody

Purification: Purified

Immunogène: Recombinant human TLR7 (451-500aa) purified from E. coli.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Détails sur TLR7

Antigène: TLR7 (Toll-Like Receptor 7 (TLR7))

Autre désignation: TLR7

Sujet: TLR7 is one of toll-like receptors which are type I transmembrane proteins involved in innate immunity byrecognizing microbial conserved structures. These proteins are characterized by multiple copies of leucine richrepeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain, and act through adaptormolecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Human TLR7(hTLR7) is predominantly expressed in lung, placenta and spleen and hTLR7, 8 genes are located on the sexchromosome X. hTLR7 may play an important role in detecting and combating viral infections.

NCBI Accession: NP_057646

Pathways: Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades