MEMO1 anticorps (AA 1-297)

N° du produit ABIN7596069

Cet anticorps Souris Monoclonal détecte spécifiquement MEMO1 dans WB, ELISA et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour MEMO1 anticorps (AA 1-297) (ABIN7596069)

Antigène: MEMO1 (Mediator of Cell Motility 1 (MEMO1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MEMO1 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Clone: AT1E9

Détail du produit anti-MEMO1 anticorps

Épitope: AA 1-297

Fonction: Human MEMO1 antibody

Purification: protein-A affinity chromatography

Immunogène: Recombinant human MEMO1 (1-297aa) purified from E. coli

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycero

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Détails sur MEMO1

Antigène: MEMO1 (Mediator of Cell Motility 1 (MEMO1))

Autre désignation: MEMO1

Sujet: MEMO1 (Mediator of ErbB2-driven cell motility 1) is a 297 amino acid protein. It is thought to relax extracellular chemotactic signals that are targeted at the microtubule cytoskeleton, thereby controlling cell migration. Additionally, MEMO1 is required for breast carcinoma migration, suggesting an important role in tumorigenesis. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity.

NCBI Accession: NP_057039