Syntaxin 6 anticorps (AA 1-239)
Aperçu rapide pour Syntaxin 6 anticorps (AA 1-239) (ABIN7599139)
Antigène
Voir toutes Syntaxin 6 (STX6) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-239
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Fonction
- Anti-Syntaxin 6/STX6 Antibody Picoband®
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-Syntaxin 6/STX6 Antibody Picoband® (ABIN7599139). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human Syntaxin 6/STX6 recombinant protein (Position: M1-A239).
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Isotype
- IgG
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Indications d'application
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Advani, R. J., Bae, H.-R., Bock, J. B., Chao, D. S., Doung, Y.-C., Prekeris, R., Yoo, J.-S., Scheller, R. H. Seven novel mammalian SNARE proteins localize to distinct membrane compartments. J. Biol. Chem. 273: 10317-10324, 1998. 2. Charest, A., Lane, K., McMahon, K., Housman, D. E. Association of a novel PDZ domain-containing peripheral Golgi protein with the Q-SNARE (Q-soluble N-ethylmaleimide-sensitive fusion protein (NSF) attachment protein receptor) protein syntaxin 6. J. Biol. Chem. 276: 29456-29465, 2001. 3. Cheng, J., Cebotaru, V., Cebotaru, L., Guggino, W. B. Syntaxin 6 and CAL mediate the degradation of the cystic fibrosis transmembrane conductance regulator. Molec. Biol. Cell 21: 1178-1187, 2010. -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Syntaxin 6 (STX6)
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Autre désignation
- STX6
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Sujet
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Synonyms: Semaphorin-3B, Sema A (V), Semaphorin-V, Sema V, SEMA3B, SEMA5, SEMAA
Tissue Specificity: Expressed abundantly but differentially in a variety of neural and nonneural tissues.
Background: Syntaxin-6 is a protein that in humans is encoded by the STX6 gene. Enables syntaxin binding activity. Involved in several processes, including Golgi ribbon formation, retrograde transport, endosome to Golgi, and vesicle fusion. Acts upstream of or within endocytic recycling. Located in several cellular components, including early endosome, perinuclear region of cytoplasm, and trans-Golgi network. Part of SNARE complex.
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Poids moléculaire
- 29 kDa
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ID gène
- 10228
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UniProt
- O43752
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Pathways
- Synaptic Vesicle Exocytosis
Antigène
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