MAPT anticorps (AA 1-322)
Aperçu rapide pour MAPT anticorps (AA 1-322) (ABIN7599268)
Antigène
Voir toutes MAPT AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-322
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Fonction
- Anti-Tau/MAPT Antibody
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-Tau/MAPT Antibody. Tested in ELISA, IF, ICC, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human Tau/MAPT recombinant protein (Position: M1-L322).
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Isotype
- IgG
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Indications d'application
- Western blot, 0.25-0.5 μg/mL, Mouse, Rat Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Date de péremption
- 12 months
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- MAPT (Microtubule-Associated Protein tau (MAPT))
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Autre désignation
- MAPT
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Sujet
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Background: MAPT, Microtubule-associated protein tau, appears to be enriched in axons. The MAPT gene is assigned to chromosome 17 by hybridization of a cDNA clone to flow-sorted and spot-blotted chromosomes and to 17q21 by in situ hybridization, containing 16 exons. The tau proteins are the product of alternative splicingfrom a single gene that in humans is designated MAPT. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons in the central nervous system and are less common elsewhere. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease.
Gene Full Name: microtubule associated protein tau
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Poids moléculaire
- 50-70 kDa
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ID gène
- 4137
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UniProt
- P10636
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Pathways
- Signalisation MAPK, Dynamique des Microtubules, M Phase, Regulation of Cell Size
Antigène
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