GLS2 anticorps (AA 1-602)

N° du produit ABIN7599493

Cet anticorps Lapin Polyclonal détecte spécifiquement GLS2 dans WB, ELISA et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour GLS2 anticorps (AA 1-602) (ABIN7599493)

Antigène: GLS2 (Glutaminase 2 (Liver, Mitochondrial) (GLS2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLS2 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-GLS2 anticorps

Épitope: AA 1-602

Fonction: Anti-GLS2 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-GLS2 Antibody Picoband® (ABIN7599493). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human GLS2 recombinant protein (Position: M1-V602).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Gomez-Fabre, P. M., Aledo, J. C., del Castillo-Olivares, A., Alonso, F. J., Nunez de Castro, I., Campos, J. A., Marquez, J. Molecular cloning, sequencing and expression studies of the human breast cancer cell glutaminase. Biochem. J. 345: 365-375, 2000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur GLS2

Antigène: GLS2 (Glutaminase 2 (Liver, Mitochondrial) (GLS2))

Autre désignation: GLS2

Sujet:

Synonyms: Cytoskeleton-associated protein 5, Colonic and hepatic tumor overexpressed gene protein, Ch-TOG, CKAP5, KIAA0097

Tissue Specificity: Expressed in fetal brain. Highly expressed in brain and placenta. Lower levels in heart, liver, thymus, kidney and lung. Located to endothelial cells and neuronal cells of the suprachiasmatic nucleus (SCN). Also detected in endothelial cells of the heart, lung and kidney. In the brain, specifically expressed in the thalamus, hippocampus and amygdala.

Background: Glutaminase 2 (liver, mitochondrial) is a protein that in humans is encoded by the GLS2 gene. The protein encoded by this gene is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. Originally thought to be liver-specific, this protein has been found in other tissues as well. Alternative splicing results in multiple transcript variants that encode different isoforms.

Poids moléculaire: 66 kDa

ID gène: 27165

Pathways: Dicarboxylic Acid Transport, L'effet Warburg