BBS1 anticorps (AA 11-275)

N° du produit ABIN7599713

L’anticorps Lapin Polyclonal anti-BBS1 a été validé pour ELISA et WB. Il convient pour détecter BBS1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour BBS1 anticorps (AA 11-275) (ABIN7599713)

Antigène: BBS1 (Bardet-Biedl Syndrome 1 (BBS1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BBS1 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-BBS1 anticorps

Épitope: AA 11-275

Fonction: Anti-BBS1 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-BBS1 Antibody Picoband® (ABIN7599713). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human ATF5 recombinant protein (Position: L11-R275). Human ATF5 shares 86.5% and 87.2% amino acid (aa) sequence identity with mouse and rat ATF5, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, Human
1. Badano, J. L., Ansley, S. J., Leitch, C. C., Lewis, R. A., Lupski, J. R., Katsanis, N. Identification of a novel Bardet-Biedl syndrome protein, BBS7, that shares structural features with BBS1 and BBS2. Am. J. Hum. Genet. 72: 650-658, 2003. 2. Badano, J. L., Kim, J. C., Hoskins, B. E., Lewis, R. A., Ansley, S. J., Cutler, D. J., Castellan, C., Beales, P. L., Leroux, M. R., Katsanis, N. Heterozygous mutations in BBS1, BBS2 and BBS6 have a potential epistatic effect on Bardet-Biedl patients with two mutations at a second BBS locus. Hum. Molec. Genet. 12: 1651-1659, 2003. 3. Beales, P. L., Badano, J. L., Ross, A. J., Ansley, S. J., Hoskins, B. E., Kirsten, B., Mein, C. A., Froguel, P., Scambler, P. J., Lewis, R. A., Lupski, J. R., Katsanis, N. Genetic interaction of BBS1 mutations with alleles at other BBS loci can result in non-mendelian Bardet-Biedl syndrome. Am. J. Hum. Genet. 72: 1187-1199, 2003.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur BBS1

Antigène: BBS1 (Bardet-Biedl Syndrome 1 (BBS1))

Autre désignation: BBS1

Sujet:

Synonyms: BBS1, BBS2L2, Bardet-Biedl syndrome 1 protein, BBS2-like protein 2

Background: Bardet-Biedl syndrome 1 protein is a protein that in humans is encoded by the BBS1 gene. Mutations in this gene have been observed in patients with the major form (type 1) of Bardet-Biedl syndrome. The encoded protein may play a role in eye, limb, cardiac and reproductive system development.

Poids moléculaire: 65 kDa

ID gène: 582

Pathways: Signalisation Hedgehog