SRI anticorps (AA 121-161)

N° du produit ABIN7599836

Cet anticorps Lapin Polyclonal détecte spécifiquement SRI dans WB, ELISA, IF, ICC et FACS. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour SRI anticorps (AA 121-161) (ABIN7599836)

Antigène: SRI (Sorcin (SRI))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRI est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Détail du produit anti-SRI anticorps

Épitope: AA 121-161

Fonction: Anti-SRI Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-SRI Antibody Picoband® (ABIN7599836). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SRI recombinant protein (Position: D121-A161).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. "Entrez Gene: SRI sorcin". 2. Meyers, M B, Pickel V M, Sheu S S, Sharma V K, Scotto K W, Fishman G I (Nov 1995). "Association of sorcin with the cardiac ryanodine receptor". J. Biol. Chem. (UNITED STATES) 270 (44): 26411-8. 3. Van der Bliek AM, Baas F, Van der Velde-Koerts T, Biedler JL, Meyers MB, Ozols RF, Hamilton TC, Joenje H, Borst P (Nov 1988). "Genes amplified and overexpressed in human multidrug-resistant cell lines". Cancer Res48 (21): 5927-32.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur SRI

Antigène: SRI (Sorcin (SRI))

Autre désignation: SRI

Sujet:

Synonyms: Sorcin, 22 kDa protein, CP-22, CP22, V19, SRI

Tissue Specificity: Detected in cardiac myocytes.

Background: Sorcin is a protein that in humans is encoded by the SRI gene. It is mapped to 7q21.1. This gene encodes a calcium-binding protein with multiple E-F hand domains that relocates from the cytoplasm to the sarcoplasmic reticulum in response to elevated calcium levels. In addition to regulating intracellular calcium homeostasis it also modulates excitation-contraction coupling in the heart. Alternative splicing results in multiple transcript variants encoding distinct proteins. Multiple pseudogenes exist for this gene.

Poids moléculaire: 22 kDa

ID gène: 6717

UniProt: P30626

Pathways: Transition Metal Ion Homeostasis, Maintenance of Protein Location, Negative Regulation of Transporter Activity