PHGDH anticorps (AA 15-533)

N° du produit ABIN7600112

Cet anticorps Lapin Polyclonal détecte spécifiquement PHGDH dans WB, ELISA, IHC, FACS, IF, IP et ICC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PHGDH anticorps (AA 15-533) (ABIN7600112)

Antigène: PHGDH (phosphoglycerate Dehydrogenase (PHGDH))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHGDH est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Détail du produit anti-PHGDH anticorps

Épitope: AA 15-533

Fonction: Anti-PHGDH Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human PHGDH shares 94.4%,94.2% amino acid (aa) sequence identity with mouse,rat PHGDH,respectively.

Attributs du produit: Anti-PHGDH Antibody. Tested in ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PHGDH recombinant protein (Position: L15-F533). Human PHGDH shares 94.4% and 94.2% amino acid (aa) sequence identity with mouse and rat PHGDH, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Immunofluorescence, 5 μg/mL, Human Immunoprecipitation, 0.5-2 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PHGDH

Antigène: PHGDH (phosphoglycerate Dehydrogenase (PHGDH))

Autre désignation: PHGDH

Sujet:

Background: This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known.

Gene Full Name: phosphoglycerate dehydrogenase

Poids moléculaire: 57 kDa

ID gène: 26227

UniProt: O43175

Pathways: Metabolism of Steroid Hormones and Vitamin D, L'effet Warburg