TLN1 anticorps (AA 1658-1876)

N° du produit ABIN7600228

L’anticorps Souris Monoclonal anti-TLN1 a été validé pour WB et FACS. Il convient pour détecter TLN1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TLN1 anticorps (AA 1658-1876) (ABIN7600228)

Antigène: TLN1 (Talin 1 (TLN1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TLN1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: 2G10D2

Détail du produit anti-TLN1 anticorps

Épitope: AA 1658-1876

Fonction: Anti-Talin 1/TLN1 Antibody Picoband® (monoclonal, 2G10D2)

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Talin 1/TLN1 Antibody Picoband® (monoclonal, 2G10D2) (ABIN7600228). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Talin 1/TLN1 recombinant protein (Position: Q1658-N1876).

Isotype: IgG1

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Rees, D. J. G., Ades, S. E., Singer, S. J., Hynes, R. O. : Sequence and domain structure of talin. Nature 347: 685-689, 1990. 2. Gilmore, A. P., Ohanian, V., Spurr, N. K., Critchley, D. R. : Localisation of the human gene encoding the cytoskeletal protein talin to chromosome 9p. Hum. Genet. 96: 221-224, 1995.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur TLN1

Antigène: TLN1 (Talin 1 (TLN1))

Autre désignation: TLN1

Sujet:

Synonyms: "chromosomal protein, Nonhistone, HMG4 antibody|High mobility group (nonhistone chromosomal) protein 4 antibody|High mobility group box 3 antibody|High mobility group protein 2a antibody|High mobility group protein 4 antibody|High mobility group protein B3 antibody| High mobility group protein HMG4 antibody|HMG 4 antibody|HMG-2a antibody|HMG-4 antibody|HMG2A antibody|HMGB 3 antibody|HMGB3 antibody| HMGB3_HUMAN antibody|MGC90319 antibody|Non histone chromosomal protein antibody|Nonhistone chromosomal protein HMG4 antibody"

Tissue Specificity: Expressed predominantly in placenta.

Background: Talin-1 is a protein that in humans is encoded by the TLN1 gene. This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin.

Poids moléculaire: 250-270 kDa

ID gène: 7094

UniProt: Q9Y490

Pathways: Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location