Hexokinase 1 anticorps (AA 17-323)

N° du produit ABIN7600258

L’anticorps anti-Hexokinase 1 Monoclonal Souris est utilisé pour la détection de Hexokinase 1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC, ICC, IF, FACS et IHC (fro).

Aperçu rapide pour Hexokinase 1 anticorps (AA 17-323) (ABIN7600258)

Antigène: Hexokinase 1 (HK1)

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Hexokinase 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 2I4

Détail du produit anti-Hexokinase 1 anticorps

Épitope: AA 17-323

Fonction: Anti-Hexokinase 1/HK1 Antibody (monoclonal, 2I4)

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Hexokinase 1/HK1 Antibody (monoclonal, 2I4) (ABIN7600258). Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Hexokinase 1/HK1 recombinant protein (Position: D17-R323).

Isotype: IgG2b

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur Hexokinase 1

Antigène: Hexokinase 1 (HK1)

Autre désignation: HK1

Sujet:

Synonyms: Hexokinase-1, Brain form hexokinase, Hexokinase type I, HK I, HK1

Tissue Specificity: Ubiquitous.

Background: Hexokinase-1 (HK1) is an enzyme that in humans is encoded by the HK1 gene on chromosome 10. It is mapped to 10q22.1. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific.

Poids moléculaire: 120 kDa

ID gène: 3098

UniProt: P19367

Pathways: Carbohydrate Homeostasis, L'effet Warburg