PMP22 anticorps (AA 117-133) (PE)

N° du produit ABIN726690

Cet anticorps anti-PMP22 est un anticorps Lapin Polyclonal détectant PMP22 dans WB. Adapté pour Humain, Rat et Souris.

Aperçu rapide pour PMP22 anticorps (AA 117-133) (PE) (ABIN726690)

Antigène: PMP22 (Peripheral Myelin Protein 22 (PMP22))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PMP22 est conjugé à/à la PE

Application: Western Blotting (WB)

Détail du produit anti-PMP22 anticorps (PE)

Épitope: AA 117-133

Réactivité croisée: Souris, Rat

Homologie: Human

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PMP-22

Isotype: IgG

Information d'application

Indications d'application: FCM: 1:20-100
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PMP22

Antigène: PMP22 (Peripheral Myelin Protein 22 (PMP22))

Autre désignation: PMP22

Sujet:

Synonyms: DSS, HNPP, CMT1A, CMT1E, GAS-3, Sp110, HMSNIA, Peripheral myelin protein 22, PMP-22, Growth arrest-specific protein 3, PMP22, GAS3

Background: PMP22 is a 22 kDa glycoprotein expressed in the compact myelin of the peripheral nervous system. In the peripheral nervous system, PMP 22 is produced by myelinating Schwann cells and is coexpressed with the genes for myelin basic protein (MBP) during nerve development and regeneration. Alterations in the level of this protein cause several genetic human diseases. If the protein is duplicated, patients develop Charcot Marie Tooth disease. If one copy of the gene is deleted, they suffer from the inherited tendency to pressure palsies.

ID gène: 5376

UniProt: Q01453