NCF1 anticorps (AA 22-384)

N° du produit ABIN7600691

Cet anticorps anti-NCF1 est un anticorps Lapin Polyclonal détectant NCF1 dans WB, ELISA, IHC, IF et FACS. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour NCF1 anticorps (AA 22-384) (ABIN7600691)

Antigène: NCF1 (Neutrophil Cytosol Factor 1 (NCF1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCF1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-NCF1 anticorps

Épitope: AA 22-384

Fonction: Anti-p47 phox/NCF1 Antibody Picoband®

Attributs du produit: Anti-p47 phox/NCF1 Antibody Picoband® (ABIN7600691). Tested in WB, IHC, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human p47 phox/NCF1 recombinant protein (Position: Q22-R384). Human NCF1 shares 81% amino acid (aa) sequence identity with both mouse and rat NCF1.

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Mouse, Rat
Immunofluorescence, 5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Del Campo, M., Antonell, A., Magano, L. F., Munoz, F. J., Flores, R., Bayes, M., Perez Jurado, L. A. Hemizygosity at the NCF1 gene in patients with Williams-Beuren syndrome decreases their risk of hypertension. Am. J. Hum. Genet. 78: 533-542, 2006. 2. Hultqvist, M., Olofsson, P., Holmberg, J., Backstrom, B. T., Tordsson, J., Holmdahl, R. Enhanced autoimmunity, arthritis, and encephalomyelitis in mice with a reduced oxidative burst due to a mutation in the Ncf1 gene. Proc. Nat. Acad. Sci. 101: 12646-12651, 2004.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur NCF1

Antigène: NCF1 (Neutrophil Cytosol Factor 1 (NCF1))

Autre désignation: NCF1

Sujet: Neutrophil cytosol factor 1, also known as p47phox, is a protein that in humans is encoded by the NCF1 gene. The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease.

Poids moléculaire: 40-50 kDa

ID gène: 653361

UniProt: P14598

Pathways: Signalisation PI3K-Akt