NAGLU anticorps (AA 24-489)

N° du produit ABIN7600838

Cet anticorps anti-NAGLU est un anticorps Lapin Polyclonal détectant NAGLU dans WB et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour NAGLU anticorps (AA 24-489) (ABIN7600838)

Antigène: NAGLU (N-Acetylglucosaminidase, alpha (NAGLU))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NAGLU est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-NAGLU anticorps

Épitope: AA 24-489

Fonction: Anti-NAGLU Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-NAGLU Antibody Picoband® (ABIN7600838). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human NAGLU recombinant protein (Position: D24-D489).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL
1. Beesley, C. E., Young, E. P., Vellodi, A., Winchester, B. G. Identification of 12 novel mutations in the alpha-N-acetylglucosaminidase gene in 14 patients with Sanfilippo syndrome type B (mucopolysaccharidosis type IIIB). J. Med. Genet. 35: 910-914, 1998. 2. Bunge, S., Knigge, A., Steglich, C., Kleijer, W. J., van Diggelen, O. P., Beck, M., Gal, A. Mucopolysaccharidosis type IIIB (Sanfilippo B): identification of 18 novel alpha-N-acetylglucosaminidase gene mutations. J. Med. Genet. 36: 28-31, 1999. 3. Chinen, Y., Tohma, T., Izumikawa, Y., Uehara, H., Ohta, T. Sanfilippo type B syndrome: five patients with an R565P homozygous mutation in the alpha-N-acetylglucosaminidase gene from the Okinawa islands in Japan. J. Hum. Genet. 50: 357-359, 2005.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur NAGLU

Antigène: NAGLU (N-Acetylglucosaminidase, alpha (NAGLU))

Autre désignation: NAGLU

Sujet:

Synonyms: NAGLU, UFHSD1, Alpha-N-acetylglucosaminidase, EC 3.2.1.50, N-acetyl-alpha-glucosaminidase, NAG [Cleaved into: Alpha-N-acetylglucosaminidase 82 kDa form, Alpha-N-acetylglucosaminidase 77 kDa form]

Background: N-acetylglucosaminidase, alpha is a protein that in humans is encoded by the NAGLU gene. This gene encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB), also known as Sanfilippo syndrome B. This disease is characterized by the lysosomal accumulation and urinary excretion of heparan sulfate.

Poids moléculaire: 82 kDa

ID gène: 4669

UniProt: P54802

Pathways: Glycosaminoglycan Metabolic Process