PRDM5 anticorps (AA 24-630)
Aperçu rapide pour PRDM5 anticorps (AA 24-630) (ABIN7600853)
Antigène
Voir toutes PRDM5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 24-630
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Fonction
- Anti-PRDM5 Antibody Picoband®
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-PRDM5 Antibody Picoband® (ABIN7600853). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human PRDM5 recombinant protein (Position: Y24-S630).
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Isotype
- IgG
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Indications d'application
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Aldahmesh, M. A., Mohamed, J. Y., Alkuraya, F. S. A novel mutation in PRDM5 in brittle cornea syndrome. (Letter) Clin. Genet. 81: 198-199, 2012. 2. Burkitt Wright, E. M. M., Spencer, H. L., Daly, S. B., Manson, F. D. C., Zeef, L. A. H., Urquhart, J., Zoppi, N., Bonshek, R., Tosounidis, I., Mohan, M., Madden, C., Dodds, A., and 11 others. Mutations in PRDM5 in brittle cornea syndrome identify a pathway regulating extracellular matrix development and maintenance. Am. J. Hum. Genet. 88: 767-777, 2011. Note: Erratum: Am. J. Hum. Genet. 89: 346 only, 2011. 3. Deng, Q., Huang, S. PRDM5 is silenced in human cancers and has growth suppressive activities. Oncogene 23: 4903-4910, 2004. -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- PRDM5 (PR Domain Containing 5 (PRDM5))
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Autre désignation
- PRDM5
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Sujet
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Synonyms: PR domain zinc finger protein 5, PR domain-containing protein 5, PRDM5, PFM2
Tissue Specificity: Widely expressed with highest levels in colon and ovary. Tends to be silenced in breast, colorectal, gastric and liver cancer tissues.
Background: PR domain zinc finger protein 5 is a protein that in humans is encoded by the PRDM5 gene. It is mapped to 4q27. The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis.
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Poids moléculaire
- 75 kDa
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ID gène
- 11107
Antigène
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