TOMM20 anticorps (AA 25-145)

N° du produit ABIN7600883

Cet anticorps anti-TOMM20 est un anticorps Lapin Polyclonal détectant TOMM20 dans WB, IF, ELISA, IHC, IP et ICC. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour TOMM20 anticorps (AA 25-145) (ABIN7600883)

Antigène: TOMM20 (Mitochondrial Import Receptor Subunit TOM20 homolog (TOMM20))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TOMM20 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Détail du produit anti-TOMM20 anticorps

Épitope: AA 25-145

Fonction: Anti-TOMM20 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-TOMM20 Antibody Picoband® (ABIN7600883). Tested in ELISA, IP, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human TOMM20 recombinant protein (Position: D25-E145).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
Immunoprecipitation, 0.5-2 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Abe, Y., Shodai, T., Muto, T., Mihara, K., Torii, H., Nishikawa, S., Endo, T., Kohda, D. Structural basis of presequence recognition by the mitochondrial protein import receptor Tom20. Cell 100: 551-560, 2000. 2. Blesa, J. R., Prieto-Ruiz, J. A., Hernandez, J. M., Hernandez-Yago, J. NRF-2 transcription factor is required for human TOMM20 gene expression. Gene 391: 198-208, 2007. 3. Goping, I. S., Millar, D. G., Shore, G. C. Identification of the human mitochondrial protein import receptor, huMas20p: complementation of delta-mas20 in yeast. FEBS Lett. 373: 45-50, 1995.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur TOMM20

Antigène: TOMM20 (Mitochondrial Import Receptor Subunit TOM20 homolog (TOMM20))

Autre désignation: TOMM20

Sujet:

Synonyms: Homeobox protein Hox-A5, Homeobox protein Hox-1C, HOXA5, HOX1C

Tissue Specificity: Ubiquitously expressed. Present at highest levels in the brain, at high levels in the placenta and testis, at intermediate levels in the intestine, ovary, skeletal muscle and thymus and at lower levels in heart, kidney, liver, lung, pancreas, prostate and spleen. In the kidney, it is widely expressed in tubules, but sparsely expressed in the glomerulus (PubMed:24676636). Expression is significantly increased in renal biopsy specimens from idiopathic FSGS (PubMed:24676636). Overexpressed in many tumor types including breast, colorectal, endometrial, hepatic, kidney, lung, ovarian and pancreatic tumors.

Background: Mitochondrial import receptor subunit TOM20 homolog is a protein that in humans is encoded by the TOMM20 gene. Enables protein-transporting ATPase activity and unfolded protein binding activity. Involved in protein targeting to mitochondrion. Located in mitochondria-associated endoplasmic reticulum membrane and mitochondrial outer membrane.

Poids moléculaire: 16 kDa

ID gène: 9804

UniProt: Q15388

Pathways: Unfolded Protein Response