SH3BP2 anticorps (AA 256-561)
Aperçu rapide pour SH3BP2 anticorps (AA 256-561) (ABIN7600936)
Antigène
Voir toutes SH3BP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 256-561
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Fonction
- Anti-3BP2/SH3BP2 Antibody
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-3BP2/SH3BP2 Antibody. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human 3BP2/SH3BP2 recombinant protein (Position: R256-R561).
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Isotype
- IgG
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Indications d'application
- Western blot, 0.25-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg /1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Date de péremption
- 12 months
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- SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))
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Autre désignation
- SH3BP2
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Sujet
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Background: SH3BP2 (SH3 domain-binding protein 2) is a protein that comes from a gene located on Chromosome 4. The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Full Name: SH3 domain binding protein 2
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Poids moléculaire
- 70 kDa
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ID gène
- 6452
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UniProt
- P78314
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Pathways
- TCR Signaling
Antigène
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