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CD79a anticorps (AA 29-220)

L’anticorps Lapin Polyclonal anti-CD79a a été validé pour FACS, IF, WB, IHC et ELISA. Il convient pour détecter CD79a dans des échantillons de Souris et Rat.
N° du produit ABIN7601110

Aperçu rapide pour CD79a anticorps (AA 29-220) (ABIN7601110)

Antigène

Voir toutes CD79a (CD79A) Anticorps
CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Reactivité

  • 218
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Souris, Rat

Hôte

  • 125
  • 101
  • 3
  • 1
  • 1
Lapin

Clonalité

  • 155
  • 75
  • 1
Polyclonal

Conjugué

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Cet anticorp CD79a est non-conjugé

Application

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Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • Épitope

    • 79
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    AA 29-220

    Fonction

    Anti-Cd79a Antibody Picoband®

    Réactivité croisée (Details)

    No cross-reactivity with other proteins.

    Attributs du produit

    Anti-Cd79a Antibody Picoband® (ABIN7601110). Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogène

    E.coli-derived mouse Cd79a recombinant protein (Position: L29-P220).

    Isotype

    IgG
  • Indications d'application

    Western blot, 0.25-0.5 μg/mL, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat
    Immunofluorescence, 2 μg/mL, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse
    ELISA, 0.1-0.5 μg/mL, -
    1. Ha, H., Kubagawa, H., Burrows, P. D. Molecular cloning and expression pattern of a human gene homologous to the murine mb-1 gene. J. Immun. 148: 1526-1531, 1992. 2. Hashimoto, S., Mohrenweiser, H. W., Gregersen, P. K., Chiorazzi, N. Chromosomal localization, genomic structure, and allelic polymorphism of the human CD79a (Ig-alpha/mb-1) gene. Immunogenetics 40: 287-295, 1994. 3. Minegishi, Y., Coustan-Smith, E., Rapalus, L., Ersoy, F., Campana, D., Conley, M. E. Mutations in Ig-alpha (CD79a) result in a complete block in B-cell development. J. Clin. Invest. 104: 1115-1121, 1999.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg NaN3.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Antigène

    CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

    Autre désignation

    Cd79a

    Sujet

    Synonyms: B-cell antigen receptor complex-associated protein alpha chain, Ig-alpha, MB-1 membrane glycoprotein, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein, CD79a, Cd79a, Iga, Mb-1

    Tissue Specificity: B-cells.

    Background: Cluster of differentiation CD79A also known as B-cell antigen receptor complex-associated protein alpha chain and MB-1 membrane glycoprotein, is a protein that in humans is encoded by the CD79A gene. It is mapped to 7 A3, 7 13.49 cM. The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.

    Poids moléculaire

    25-30 kDa

    ID gène

    12518

    UniProt

    P11911

    Pathways

    BCR Signaling
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