PHF21B anticorps (AA 291-499)

N° du produit ABIN7601150

Cet anticorps anti-PHF21B est un anticorps Lapin Polyclonal détectant PHF21B dans WB, IF, ELISA et ICC. Adapté pour Humain.

Aperçu rapide pour PHF21B anticorps (AA 291-499) (ABIN7601150)

Antigène: PHF21B (PHD Finger Protein 21B (PHF21B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHF21B est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)

Détail du produit anti-PHF21B anticorps

Épitope: AA 291-499

Fonction: Anti-PHF21B Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-PHF21B Antibody Picoband® (ABIN7601150). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PHF21B recombinant protein (Position: E291-M499).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bergamo, N. A., da Silva Veiga, L. C., dos Reis, P. P., Nishimoto, I. N., Magrin, J., Kowalski, L. P., Squire, J. A., Rogatto, S. R. Classic and molecular cytogenetic analyses reveal chromosomal gains and losses correlated with survival in head and neck cancer patients. Clin. Cancer Res. 11: 621-631, 2005. 2. Bertonha, F. B., Barros Filho, M. deC., Kuasne, H., dos Reis, P. P., da Costa Prando, E., Munoz, J. J. A. M., Roffe, M., Hajj, G. N. M., Kowalski, L. P., Rainho, C. A., Rogatto, S. R. PHF21B as a candidate tumor suppressor gene in head and neck squamous cell carcinomas. Molec. Oncol. 9: 450-462, 2015. 3. Reis, P. P., Rogatto, S. R., Kowalski, L. P., Nishimoto, I. N., Montovani, J. C., Corpus, G., Squire, J. A., Kamel-Reid, S. Quantitative real-time PCR identifies a critical region of deletion on 22q13 related to prognosis in oral cancer. Oncogene 21: 6480-6487, 2002.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur PHF21B

Antigène: PHF21B (PHD Finger Protein 21B (PHF21B))

Autre désignation: PHF21B

Sujet:

Synonyms: Kelch repeat and BTB domain-containing protein 2, BTB and kelch domain-containing protein 1, KBTBD2, BKLHD1, KIAA1489

Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Background: PHF21B (PHD finger protein 21B), also known as PHF4, is a 531 amino acid protein that contains one PHD-type zinc finger and is expressed as multiple alternatively spliced isoforms. The gene encoding PHF21B maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, neurofibromatosis type 2, autism and schizophrenia.

Poids moléculaire: 57 kDa

ID gène: 112885