Kallikrein 7 anticorps (AA 30-238)
Aperçu rapide pour Kallikrein 7 anticorps (AA 30-238) (ABIN7601217)
Antigène
Voir toutes Kallikrein 7 (KLK7) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 30-238
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Fonction
- Anti-Klk7 Antibody
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-Klk7 Antibody (ABIN7601217). Tested in ELISA, IHC, WB applications. This antibody reacts with Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived rat Klk7 recombinant protein (Position: K30-N238).
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Isotype
- IgG
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Indications d'application
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Western blot, 0.25-0.5 μg/mL, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Rat
ELISA, 0.1-0.5 μg/mL, Rat
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Kallikrein 7 (KLK7)
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Autre désignation
- Klk7
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Sujet
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Synonyms: Platelet basic protein, PBP, C-X-C motif chemokine 7, Leukocyte-derived growth factor, LDGF, Macrophage-derived growth factor, MDGF, Small-inducible cytokine B7, PPBP, CTAP3, CXCL7, SCYB7, TGB1, THBGB1, NAP-2
Background: Kallikrein-related peptidase 7 (KLK7) is a serine protease that in humans is encoded by the KLK7 gene. KLK7 is a chymotrypsin-like serine protease of the member of peptidase S1 family. It is synthesized with a signal peptide of 22 amino acids (aa 1-22) and a propeptide region (aa 23-29) that are subsequently cleaved to generate the mature form. Human KLK7 displays about 40 to 60 % amino acid homology with other members of the family. It cleaves proteins with aromatic side chains in the P1 position. KLK7 is abundantly expressed in the skin and is also present in the brain, mammary gland, cerebellum, spinal cord, and kidney. Lower levels of expression have been reported in in salivary glands, uterus, thymus, thyroid, placenta, trachea, and testis. Its levels are shown to be up-regulated in ovarian carcinoma, especially late-stage serous carcinoma. Less differentiated tumors of more advanced stage show higher level KLK7 expression. KLK7 activity is inhibited by zinc and copper ions
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Poids moléculaire
- 38 kDa
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ID gène
- 292852
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UniProt
- P36373
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Pathways
- Système du Complément
Antigène
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